Mainframes and batch programming
Early programs were submitted as decks of punched cards and run in batches, often overnight, so a single typo could cost a programmer an entire day waiting for the next run. Mathematicians, and in large numbers women, moved from hand computation straight into this new 'programming' work, since it was seen as clerical and detail-oriented rather than prestigious. FORTRAN (1957) and COBOL (1959) took hold in this decade, and the sheer difficulty of building reliable large systems on this hardware set up the 'software crisis' the next era would try to name and fix.