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Ronald Fisher
British statistician and geneticist who built much of the modern framework of applied statistics — analysis of variance, randomized experimental design and maximum likelihood estimation — largely while analyzing decades of crop-yield trials at Rothamsted Experimental Station in the 1920s.
At a Rothamsted afternoon tea in the late 1920s, colleague Muriel Bristol claimed she could tell whether milk had been poured into a cup before or after the tea. Rather than dismiss her, Fisher designed a randomized experiment to actually test the claim — the scenario he later used in his 1935 book 'The Design of Experiments' to lay out the logic of the null hypothesis and randomized trial design.
“A rigorous experiment needs a control and randomization built in from the start, not argued about afterward.”