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TTuberculosis: discoveries and programmes

Tuberculosis ? An airborne bacillus of latency and long care — programmes and air, not a drug recipe.

Sanatoria and mountain air were culture before drugs. Then soil chemistry gave streptomycin in 1944 and combination therapy followed.

WHO's late-20th-century DOTS strategy treated TB as a management problem of completing courses.

Timeline

1882Koch's announcement

The bacillus is shown; germ theory gains a famous chronic disease.

1895X-ray lungs

Roentgen's rays later let clinics see cavities without opening the chest.

1921BCG first infant

An attenuated vaccine begins a century of childhood programmes.

1944Streptomycin

A soil-microbe drug first hits TB — resistance appears if it is used alone.

1952Isoniazid era

Combination oral therapy begins to empty sanatoria in rich countries.

1993WHO emergency

WHO declares TB a global emergency as HIV and neglect reverse gains.

1995DOTS strategy

A five-element programme standardizes finding cases and supporting treatment.

2010s-20sNew tools

Molecular tests and new drugs shorten some resistant courses — still specialist care.

The timeline names turning points, not today's pill list.

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