Skip to content

THow tuberculosis persists

Tuberculosis ? An airborne bacillus of latency and long care — programmes and air, not a drug recipe.

Bacilli that reach alveoli may be eaten by macrophages and still survive inside them — a slow intracellular story.

Infectiousness is mainly from people with active pulmonary disease who cough. Latent infection is not a cough factory.

Parts

Mycolic wall

The lipid-rich envelope is a fortress and a reason growth is slow.

Macrophage niche

The bacillus can live inside the very cell sent to kill it.

Cavity

In some lungs, holes become factories of airborne nuclei.

Lymph travel

Bacilli can leave the lung and seed other organs.

Slow generation

Division measured in hours to days, not minutes like E. coli in broth.

Persisters

Sheltered cells help explain why programmes talk in months, not days.

Life cycle

1Inhale nuclei

Shared indoor air delivers a small infectious dose to a new host.

2Contain or progress

Most infections are contained. Some become primary disease, especially in children.

3Latency years

Bacilli may sit quietly while the person feels well.

4Active cough

If disease wakes in the lung, months of care and infection-control follow — clinically directed.

No culture or drug-recipe steps are given.

Keep exploring

More in Encounters