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TOpen questions about tuberculosis

Tuberculosis ? An airborne bacillus of latency and long care — programmes and air, not a drug recipe.

Researchers want vaccines that protect adult lungs better than BCG and tests that find infectious people faster.

Shorter regimens exist in specialist guidelines. They are not copied here as instructions.

Open questions

Can we replace BCG?

Candidates are in trials. None is a do-it-yourself product.

Who will progress from latency?

Better biomarkers would spare unneeded preventive therapy. Research continues.

How short can safe therapy be?

Trials keep testing shorter combinations. Answers belong in specialist care.

How do we cut stigma?

Confidential testing and language that names a bacterium, not a character flaw.

What about zoonotic TB?

M. bovis still matters where unpasteurized milk and infected cattle meet people.

The frontier is ending transmission, not a home laboratory.

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