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HOpen questions about H. pylori

Helicobacter pylori ? A gastric spiral that rewrote the ulcer textbook — Nobel 2005, Korea's high historic prevalence, no recipes.

Resistance to common eradication drugs is rising in some regions. That is why regimens are not copied here — they change and they are clinical.

Whether mass screen-and-treat lowers gastric cancer enough to justify costs is a live East Asian policy debate.

Open questions

Who should be tested in low-prevalence countries?

Dyspepsia pathways differ. Guidelines, not blogs, set the default.

How do we keep eradication working?

Stewardship and local resistance maps matter. Recipes are omitted here.

Does treating everyone cut cancer enough?

Models and trials in East Asia are watched. Answers are policy-scale.

What is the role of CagA-negative strains?

Risk is not uniform. Strain talk belongs in research and specialist care.

Can we vaccinate?

Vaccine research exists. No routine global shot is standard as of the mid-2020s.

The frontier is smarter testing, not backyard isolates.

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