Parkinson’s disease
BG gating failure: bradykinesia, rigidity, tremor.
Motor Control · From intention to muscle — cortico-basal ganglia-cerebellar loops that select, time and correct movement.
Reviewed 2026-08·Sources & research·Methodology·Media credits
Clinical relevance spans Parkinson’s, stroke, cerebellar ataxia, dystonia, apraxia and spinal injury — always within a broader assessment.
Educational neuroscience context only — not medical advice or diagnosis.
BG gating failure: bradykinesia, rigidity, tremor.
Weakness, spasticity and lost fractionation.
Dysmetria and timing errors from prediction loss.
Overflow and abnormal sensorimotor maps.
Skilled gesture failure despite intact strength.
Interrupted descending drive and reflex imbalance.
Slowed initiation and scaling of movement.
Overshoot and oscillation near targets.
Sudden failure to initiate or continue steps.
Velocity-dependent resistance after upper-motor injury.
Independent digit control collapses.
When indicated for Parkinsonian gating failure.
High-dose practice of meaningful actions.
Drive use-dependent cortical remapping post-stroke.
Recalibrate impedance and anticipatory posture.
Seek licensed clinicians for personal symptoms; device demos are not diagnoses.
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