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BBacteriophages history — Twort, d’Hérelle and phage therapy eras

Bacteriophages — Viruses that infect bacteria — Earth's most abundant biological entities, and a concept-level idea in medicine.

At a glance
Timeline

Milestones in order. This is history, not a weekly activity grid.

1915 Twort's glassy colonies19151917 d'Hérelle names phage19171920s Eliava Institute1920s1940s Luria–Delbrück1940s1952 Hershey–Chase19521961 MS2 RNA phage19612007 CRISPR spacer proof20072010s Compassionate phage cases2010s
  1. Twort's glassy colonies
  2. d'Hérelle names phage
  3. Eliava Institute
  4. Luria–Delbrück
  5. Hershey–Chase
  6. MS2 RNA phage
  7. CRISPR spacer proof
  8. Compassionate phage cases
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Darker cells mean a higher score for this topic on that metric.

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Read Identity → How they live → Body & health, then use compare rails.

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Public-health education — not a care plan, prescription, or outbreak briefing.

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It names everyday desks for Tree of microbes before English norms look universal.

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How they live and Body & health carry mechanisms; skim Identity first.

Start with this section - History

Bacteriophage history runs from Twort (1915) and Félix d’Hérelle (1917) through mid-century clinical use and today’s sequencing-era revival. Independent observations in 1915–1917 showed something that ate bacterial colonies. Félix d'Hérelle named bacteriophage and tried therapy before antibiotics existed.

Western clinics largely switched to antibiotics after the 1940s. The Soviet and Georgian schools kept phage collections. Molecular biology was born in phage labs in between.

Timeline

1915Twort's glassy colonies

Frederick Twort describes glassy dissolution of micrococci — an early phage observation.

1917d'Hérelle names phage

Félix d'Hérelle coins bacteriophage and begins therapeutic attempts in Paris.

1920sEliava Institute

George Eliava's Tbilisi school builds a lasting phage-medicine tradition.

1940sLuria–Delbrück

Fluctuation tests with phages prove bacterial mutations are random, not directed.

1952Hershey–Chase

T2 blender experiments settle DNA as hereditary material.

1961MS2 RNA phage

A tiny RNA phage becomes a model; its genome is later the first fully sequenced (1976).

2007CRISPR spacer proof

Barrangou and colleagues show spacers confer phage resistance in Streptococcus thermophilus.

2010sCompassionate phage cases

Documented last-resort cases return phage therapy to Western journals — still not a home kit.

Today's headlines recycle an old idea with new sequencing. The ethics stay clinical, not do-it-yourself.

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