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Frontiers

Brain Aging · Lifelong change in structure, networks and cognitive reserve.

Reviewed 2026-08·Sources & research·Media credits

Open questions still driving Brain Aging research.

Tech and ethics sit beside mechanism.

Open questions

Open question 1

An active debate about reserve and network change.

Open question 2

An active debate about reserve and network change.

Open question 3

An active debate about reserve and network change.

Open question 4

An active debate about reserve and network change.

Open question 5

An active debate about reserve and network change.

Technology

Technology 1

An emerging approach for Brain Aging.

Technology 2

An emerging approach for Brain Aging.

Technology 3

An emerging approach for Brain Aging.

Technology 4

An emerging approach for Brain Aging.

Technology 5

An emerging approach for Brain Aging.

Ethics

Ethics 1

An ethical tension around reserve and network change.

Ethics 2

An ethical tension around reserve and network change.

Ethics 3

An ethical tension around reserve and network change.

Frontiers change quickly; treat claims as living context.

Sources & research

  1. What is cognitive reserve? Theory and research application of the reserve conceptStern Y · 2002 · Journal of the International Neuropsychological SocietyDOIPubMed
  2. Aging of the brain and cognitive declinePark DC; Reuter-Lorenz P · 2009 · Annual Review of PsychologyDOIPubMed
  3. The aging brain: functional adaptation across adulthoodCabeza R; et al. · 2018 · Nature Reviews NeuroscienceDOI

Media credits

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