Gut residents
Help digest fibres, make some vitamins, and crowd out some pathogens.
Bacteria ? Single-celled prokaryotes with cell walls ? the oldest widespread life form, and both partners and pathogens.
A healthy person is an ecosystem. Barrier surfaces carry dense communities that train immunity and occupy niches invaders want.
Pathogenesis is ecology gone wrong for us: toxins, invasion, inflammation. Most bacterial cells you meet never cross that line.
Help digest fibres, make some vitamins, and crowd out some pathogens.
Acid and occupancy make it harder for opportunists to bloom.
Broken barriers let environmental or resident species reach tissue and blood.
Sometimes the molecule ? tetanus toxin, cholera toxin ? does the damage more than the cell count.
Early-life exposure patterns shape tolerance; the story is still being rewritten.
Broad-spectrum antibiotics save lives and also prune allies; stewardship is the compromise.
Handwashing, vaccines and antibiotics are tools with different jobs ? none of them mean 'delete all bacteria'.
Packets of DNA or RNA that are not cells — they replicate only inside living hosts.
Familiarity 96A eukaryotic kingdom of yeasts, moulds and mushrooms — chitin walls, external digestion, partners of plants.
Familiarity 80A prokaryotic domain that is not bacteria — methanogens, extremophiles and no known human pathogens.
Familiarity 35Viruses that infect bacteria — Earth's most abundant biological entities, and a concept-level idea in medicine.
Familiarity 42Motile unicellular eukaryotes — a teaching grade that includes pond ciliates and a minority of serious parasites.
Familiarity 58