Precision exposure
Can biomarkers guide inhibitory-learning parameters?
Open questions include personalising exposure, digital therapeutics evidence and how to prevent relapse without endless avoidance.
Educational neuroscience context only — not medical advice, diagnosis or a substitute for emergency or clinical care. If you are in crisis, seek local emergency services or a licensed clinician.
Open questions
Digital CBT quality
Which apps match therapist-led outcomes?
Relapse mechanisms
Why does threat learning return under stress?
Culture & stigma
How do norms shape help-seeking and symptom language?
Psychedelic-assisted trials
Promise versus risk for anxiety indications?
Technology
VR exposure platforms
Controlled graded cues with therapist oversight.
Just-in-time adaptive interventions
Phone prompts timed to rising arousal — need evidence.
Wearable arousal sensing
Detect spirals early without surveillance abuse.
Neurofeedback (sham-controlled)
Test whether signal learning beats expectancy.
Closed-loop neuromodulation research
Experimental only; not consumer therapy.
Ethics
Pathologising normal fear
Not every worry needs a disorder label.
App data privacy
Mood logs can be sold or breached.
Access equity
Evidence-based care must not be luxury-only.
Prefer evidence and clinicians over anxiety-app marketing.
Sources & research
- Anxiety disordersPrimer on anxiety disorders and mechanisms.DOI
- Using Neuroscience to Help Understand Fear and Anxiety: A Two-System FrameworkTwo-system framing of fear vs anxiety circuits.DOI
- Epidemiology of anxiety disorders in the 21st centuryEpidemiology of anxiety disorders.DOI
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