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Intracranial EEG · Electrocorticography and depth electrodes — millimetre-scale human recordings that reveal high-frequency dynamics surgery can see.

Reviewed 2026-08·Sources & research·Methodology·Media credits

Wilder Penfield
Intracranial EEGUnited States National Library of Medicine · Public domain · Wikimedia Commons

Methods include implantation planning, continuous video-EEG, cortical stimulation, high-gamma analytics and careful statistics under sparse sampling.

Triangulate with imaging and behaviour; do not overclaim from a few contacts.

Tools

ECoG grids / strips

Surface sampling for mapping and research.

SEEG depth electrodes

3D network coverage with smaller openings.

Video-EEG monitoring units

Capture seizures with behavioural context.

Cortical stimulation systems

Causal mapping of language and motor function.

High-gamma / time-frequency toolkits

Extract task-related broadband power.

MRI co-registration

Locate contacts in individual anatomy.

Protocols

Pre-implant multimodal conference

Align hypotheses before electrode placement.

Ictal onset review boards

Consensus reading of seizure starts.

Cognitive task batteries (optional)

Only when clinically compatible and consented.

Sham / control contrasts in research

Guard against arousal confounds in high-gamma.

Limits

Sampling bias

Clinical targets ≠ random brain coverage.

Pathology confounds

Epileptic tissue may alter “normal” dynamics.

Generalisation limits

Findings from few patients need replication.

Preregister cognitive analyses when possible; clinical care comes first.

Sources & research

  1. Promises and limitations of human intracranial electroencephalographyParvizi J; Kastner S · 2018 · Nature NeurosciencePromises and limits of human iEEG.DOI
  2. High-frequency neural activity and human cognition: past, present and possible future of intracranial EEG researchLachaux JP; et al. · 2012 · Progress in NeurobiologyHigh-frequency activity and cognition review.DOI
  3. High-frequency gamma oscillations and human brain mapping with electrocorticographyCrone NE; et al. · 2006 · Progress in Brain ResearchHigh-gamma mapping with ECoG.DOI

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