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🔌Anatomy

Intracranial EEG · Electrocorticography and depth electrodes — millimetre-scale human recordings that reveal high-frequency dynamics surgery can see.

Reviewed 2026-08·Sources & research·Methodology·Media credits

Intracranial EEG
Intracranial EEGBruceBlaus . When using this image in external sources it can be cited as: Blausen.com staff (2014). " Medical gallery of Blausen Medical 2014 ". WikiJournal of Medicine 1 (2). DOI : 10.15347/wjm/2014.010 . ISSN 2002-4436 . · CC BY 3.0 · Wikimedia Commons

“Anatomy” here is electrode anatomy: grids on gyral surfaces, strips in sulci and depth leads targeting deep nodes like hippocampus or insula.

Signal sources are local field potentials summing synaptic currents — not single spikes unless dedicated microelectrodes are used.

Structures

Cortical surface (ECoG sites)

Gyral recordings for language, motor and seizure mapping.

Hippocampus / MTL (depth)

Common SEEG targets for temporal lobe epilepsy and memory tasks.

Insula

Deep coverage for seizures and interoceptive paradigms.

Sensorimotor cortex

High-gamma mapping of movement and somatotopy.

Language cortex (STG / IFG)

Eloquent-area mapping before resection.

Thalamic / deep nuclei (selected)

Occasional depth targets for network seizures or DBS planning.

Pathways

Local cortical circuits

Primary generators of high-gamma task responses.

Cortico-cortical white matter

Propagates seizures and task-related coherence.

Hippocampal–neocortical loops

Memory encoding dynamics visible on depth leads.

Thalamocortical relays

Contribute to rhythms and some seizure networks.

Landmarks

Grid implantation surgery

Clinical gateway to surface recordings.

SEEG trajectory planning

MRI-guided paths through networks of interest.

Cortical stimulation mapping

Causal probe of language and motor sites.

High-gamma task epochs

Analytic window for cognitive iEEG studies.

Open atlas neighbours: cortex, hippocampus, insula, thalamus.

Sources & research

  1. Promises and limitations of human intracranial electroencephalographyParvizi J; Kastner S · 2018 · Nature NeurosciencePromises and limits of human iEEG.DOI
  2. High-frequency neural activity and human cognition: past, present and possible future of intracranial EEG researchLachaux JP; et al. · 2012 · Progress in NeurobiologyHigh-frequency activity and cognition review.DOI
  3. High-frequency gamma oscillations and human brain mapping with electrocorticographyCrone NE; et al. · 2006 · Progress in Brain ResearchHigh-gamma mapping with ECoG.DOI

Media credits

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