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Addiction · Compulsive seeking when reward prediction and control circuits tip.

Reviewed 2026-08·Sources & research·Media credits

Santiago Ramón y Cajal
AddictionOriginal photo is anonymous although published by Clark University in 1899. Restoration by Garrondo · Public domain · Wikimedia Commons

Clinical notes for Addiction are educational — never a substitute for care.

Signs highlight patterns clinicians watch for.

Conditions

Condition 1

A clinical pattern linked to reward learning gone sticky.

Condition 2

A clinical pattern linked to reward learning gone sticky.

Condition 3

A clinical pattern linked to reward learning gone sticky.

Condition 4

A clinical pattern linked to reward learning gone sticky.

Condition 5

A clinical pattern linked to reward learning gone sticky.

Condition 6

A clinical pattern linked to reward learning gone sticky.

Signs

Sign 1

A sign cluster often discussed with Addiction.

Sign 2

A sign cluster often discussed with Addiction.

Sign 3

A sign cluster often discussed with Addiction.

Sign 4

A sign cluster often discussed with Addiction.

Sign 5

A sign cluster often discussed with Addiction.

Care themes

Care theme 1

Evidence-informed care theme (rehab, medication, support, monitoring).

Care theme 2

Evidence-informed care theme (rehab, medication, support, monitoring).

Care theme 3

Evidence-informed care theme (rehab, medication, support, monitoring).

Care theme 4

Evidence-informed care theme (rehab, medication, support, monitoring).

Seek licensed care for personal symptoms; this atlas does not diagnose.

Sources & research

  1. Neural systems of reinforcement for drug addictionEveritt BJ; Robbins TW · 2005 · Nature NeuroscienceDOIPubMed
  2. The neural basis of addictionKoob GF; Volkow ND · 2010 · NeuropsychopharmacologyDOIPubMed
  3. Addiction as a brain disease revisedHeilig M; et al. · 2021 · NeuropsychopharmacologyDOIPubMed

Media credits

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