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Bipolar Disorder · Mania, depression and the networks between — mood-state biology, sleep disruption and evidence-based stabilising care.

Reviewed 2026-08·Sources & research·Methodology·Media credits

John Cade
Bipolar DisorderAustralian Information Service · Public domain · Wikimedia Commons

Eight voices who shaped mood-stabiliser science, neuroimaging and clinical guidelines for bipolar disorder.

Portraits resolve via Wikimedia when licences allow.

People

01 John Cade

John Cade

1912–1980 · Australia

Lithium

Introduced lithium into modern psychiatry.

02 Mogens Schou

Mogens Schou

1918–2005 · Denmark

Lithium trials

Rigorous evidence for lithium prophylaxis.

03 Emil Kraepelin

Emil Kraepelin

1856–1926 · Germany

Manic-depressive

Classic nosology separating manic-depressive illness.

04 Kay Redfield Jamison

Kay Redfield Jamison

b. 1946 · USA

Lived expertise

Clinician–scholar bridging science and experience.

05 Bipolar disorder

Mary Phillips

20th–21st c. · UK/USA

Neuroimaging

Influential imaging work on bipolar emotion circuitry.

06 Bipolar

Guy Goodwin

b. 1947 · UK

Guidelines

Evidence-based psychopharmacology guidance.

07

Ellen Frank

b. 1944 · USA

IPSRT

Interpersonal and social rhythm therapy pioneer.

08

Frederick Goodwin

1936–2020 · USA

Bipolar science

Major syntheses of manic-depressive illness biology and care.

Read primary papers; this page is not care.

Sources & research

  1. Bipolar disorderGrande I; et al. · 2016 · The LancetClinical primer on bipolar disorder.DOI
  2. A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitryPhillips ML; Swartz HA · 2014 · American Journal of PsychiatryCritical neuroimaging synthesis for bipolar circuitry.DOI
  3. Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for PsychopharmacologyGoodwin GM; et al. · 2016 · Journal of PsychopharmacologyEvidence-based treatment guidelines.DOI

Media credits

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